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Abstract

AN EFFICIENT PROTOCOL FOR THE SYNTHESIS OF TETRAZOLE VIA BASE CATALYZED UGI-TYPE MCR

Mayur K. Shiyal and Yogesh T. Naliapara*

ABSTRACT

Numerous diversity-oriented synthesis of tetrazole heterocycles have been demonstrated but most of them are based on point diversity within the same library and usually include slow sequential multistep synthesis, which also hurt from low yields and/or poor originator scopes. In current context, an efficient synthesis has been developed with the use of methenol under catalytically free reaction conditions.

Keywords: four -component condensation, tetrazole, Ugi-Type MCR.


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