Abstract

TO ANALYSE THE RISK FACTOR AND DRUG UTILIZATION REVIEW OF PEPTIC ULCER DISEASE IN A TERTIARY CARE HOSPITAL

*Pooja Chandran, K. C. Arul Prakasam, Abhirami Jayachandran, Ann Mary Joseph and Sirajul Muneer M. A.

ABSTRACT

Peptic ulcer disease is defined as disruption of the mucosal integrity of the stomach or duodenum thereby resulting in a defect or excavation occurring locally due to the presence of an active inflammation.[1] About 10% of people develops a peptic ulcer at some point in their life.[3] A prospective observational study was conducted among both inpatients and outpatients (both male and female) in general medicine and gastroenterology of a Tertiary Care Hospital, Erode. A total number of 110 patients were enrolled in the study. Informed consent forms were taken from every patient after the procedure is being explained. The study aims to identify risk factors for PUD and estimate their relative impact on ulcer incidence in patients and to evaluate the drug utilization pattern of anti peptic drugs. From the study it may be concluded that the mostly prescribed anti-peptic ulcer agent in our hospital is Pantoprazole (54.61%) and Food habits (47.44%) are the main risk factor in peptic ulcer disease.

Keywords: Peptic ulcer disease, Risk factor, Drug Utilisation Evaluation, Anti peptic ulcer drugs.