Abstract

A REVIEW STUDY ON CLINICAL PROFILE OF NON ALCOHOLIC FATTY LIVER (NAFLD)

Sk Jareena*, Sk Hafeezunnisa, Sreenu Thalla and Padmalatha Kantamneni

ABSTRACT

Introduction: Non-alcoholic fatty liver disease is the condition in which hepatic accumulation is present these include liver disease caused by other factors, excessive alcohol consumption and other condition that may lead to hepatic steatosis. Methodology: Study 1 is a cross-sectional, prospective study that was conducted at Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India for a period of 5 months. The study included a total of 140 patients with Type 2 diabetes mellitus in the age group of 20-70 years, attending a medical outpatient clinic. study 2 is a prospective study, a total of 100 patients with Type-2 DM study population was included the age group of 20-70 years, attending a medical outpatient clinic. prospective study 3 was designed to enroll known T2DM patients (duration ≥3 years), in the age group of 25-65 years, attending an outpatient Medicine department of Dr. D. Y. Patil Medical College, Kolhapur, a tertiary care Centre. study 4 Study subjects were participants in the Valpolicella Heart Diabetes Study, a prospective observational study designed primarily to evaluate associations between type 2 diabetes and the incidence of chronic vascular complications. Study 5 participants in the Valpolicella Heart Diabetes Study. Briefly, we enrolled all of type 2 diabetic outpatients (n 2,103) who regularly attended our clinic in the period. Discussion: Hepatic steatosis and steatohepatitis can occur in association with a numerous disease affecting the liver including hepatitis A, hepatitis B, and C, autoimmune hepatitis, hypothyroidism, and hemochromatosis, however, much of the increase in the prevalence of NAFLD is driven by its pathophysiologic and epidemiologic connection to type 2 diabetes mellitus and obesity. Conclusion: Gender distribution of NAFLD in T2DM for study 1 having less incidence of fatty liver than study 2. Age distribution of NAFLD in Type- 2 DM patients of study 1 is better than study 2 and study 3 because the population with fatty liver is less in number. Study 4 is more significant than study 5 in its respective parameters.

Keywords: NAFLD, DM, Hepaticsteatosis, Steatohepatitis.