A REVIEW STUDY ON CLINICAL PROFILE OF NON ALCOHOLIC FATTY LIVER (NAFLD)
Sk Jareena*, Sk Hafeezunnisa, Sreenu Thalla and Padmalatha Kantamneni
ABSTRACT
Introduction: Non-alcoholic fatty liver disease is the condition in
which hepatic accumulation is present these include liver disease
caused by other factors, excessive alcohol consumption and other
condition that may lead to hepatic steatosis. Methodology: Study 1 is a
cross-sectional, prospective study that was conducted at Indira Gandhi
Institute of Medical Sciences, Patna, Bihar, India for a period of 5
months. The study included a total of 140 patients with Type 2
diabetes mellitus in the age group of 20-70 years, attending a medical
outpatient clinic. study 2 is a prospective study, a total of 100 patients
with Type-2 DM study population was included the age group of 20-70
years, attending a medical outpatient clinic. prospective study 3 was
designed to enroll known T2DM patients (duration ≥3 years), in the
age group of 25-65 years, attending an outpatient Medicine department of Dr. D. Y. Patil
Medical College, Kolhapur, a tertiary care Centre. study 4 Study subjects were participants in
the Valpolicella Heart Diabetes Study, a prospective observational study designed primarily
to evaluate associations between type 2 diabetes and the incidence of chronic vascular
complications. Study 5 participants in the Valpolicella Heart Diabetes Study. Briefly, we
enrolled all of type 2 diabetic outpatients (n 2,103) who regularly attended our clinic in the
period. Discussion: Hepatic steatosis and steatohepatitis can occur in association with a
numerous disease affecting the liver including hepatitis A, hepatitis B, and C, autoimmune
hepatitis, hypothyroidism, and hemochromatosis, however, much of the increase in the
prevalence of NAFLD is driven by its pathophysiologic and epidemiologic connection to type
2 diabetes mellitus and obesity. Conclusion: Gender distribution of NAFLD in T2DM for
study 1 having less incidence of fatty liver than study 2. Age distribution of NAFLD in Type- 2 DM patients of study 1 is better than study 2 and study 3 because the population with fatty liver is less in number. Study 4 is more significant than study 5 in its respective parameters.
Keywords: NAFLD, DM, Hepaticsteatosis, Steatohepatitis.
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