SPECTROPHOTOMETRIC DETERMINATION OF HALOPERIDOL IN PHARMACEUTICAL FORMULATIONS
D. Venkateswarlu*, G. Sreedevi, I. E. Chakravarthy and N. Rami Reddy
ABSTRACT
A simple, sensitive, rapid and accurate colorimetric method has been
developed for the estimation of haloperidol in pharmaceutical
formulations. The proposed method was based on the formation of
chloroform extractable complex of haloperidol with phenol red. The
absorbance of the extractable ion pair complex is measured at the
wavelength of maximum absorbance 485 nm against the reagent blank.
Results obtained are statistically validated and found to be
reproducible.
Keywords: Spectrophotometry, phenol red, haloperidol, Pharmaceutical and Formulation.
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