FORMULATION AND EVALUATION OF FAST DISSOLVING TABLETS OF CHARANTIN USING TWO DIFFERENT TECHNUQUES
H. M. Meghana* and J. Adlin Jino Nesalin
ABSTRACT
Fast dissolving tablets considered as an innovative dosage form to
avoid the problem of swallowing and to provide quick onset of action.
Here Charantin containing fast dissolving tablets were prepared by
using two different techniques i.e., direct compression and sublimation
method. All the formulations in both methods prepared by using three
different superdisintegrants viz Crospovidone, Croscarmellose sodium
and sodium starch glycolate in 5% and 10% concentration. And in
sublimation technique Camphor used as sublimating agent. Then all
the prepared formulation was evaluated for certain pre formulation
parameters and also post formulation parameters. Comparative study
of two different methods shows that sublimation method is a better
alternative to direct compression technique.
Keywords: Charantin, Crospovidone, Croscarmellose sodium, Sodium starch glycolate, Direct compression method, Sublimation method.
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