WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

ADMET & CYTOTOXICITY PREDICTION OF RED SEAWEED GRACILLARIA DURA: AN IN SILICO APPROACH

Nikunj B. Patel, Lensi N. Patel, Khushi D. Patel, Maitri V. Patel and Haresh S. Kalasariya*

ABSTRACT

In the present study, marine red algae Gracillaria dura was selected from the study performed by Biji Cyriac and K. Eswaran (2015). The screening of phycocompounds was carried out by using GCMS analysis from which a total of 10 compounds selected for this study. Chemical structure details (such as molecular weight, CAS, EC number, SMILE file etc.) of selected phycocompounds obtained from PubChem database. Prime requisite ADMET properties were predicted by using Danish (Q)SAR. Then, toxicity prediction was done by using ProTox-II whereas cytotoxicity (for both normal and cancerous cell line) prediction was carried out by using online webtool CLC Pred. The above study showed that the Ethyl cholate and Squalene compound can be applied as a drug candidate as well as further pharmacological evaluation.

Keywords: Gracillaria dura, Toxicity, ProTox-II, In-silico, Phycocomopund.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More