NANO FORMUATIONS: PREPARATIONS AND STABILITY CHALLENGES
Habeeba T. U., Nishad K. M.*, Sirajudheen M. K. and Shiji Kumar P. S.
ABSTRACT
Nano drug delivery system is engineered technologies that use
nanoparticle size ranges from 1-100nm to the target drug delivery by
controlled release of therapeutic agent. This modern form of a drug
delivery system reduce both dosage and dosage frequency. Novel drug
delivery system is that it is ahead of conventional dossage forms, it
bring forth optimum dose at the right time and right location, well
regulated use of exorbitant drugs and excipients, depletion on
production cost, advantages to patients, superior therapy.
Nanoformulations are formulations of nano medicine. The nano
medicine compass nanoparticles for the treatment and diagnosis of
disease in more efficacious way. The drug is loaded on the nano carrier
which are used for the dispatch of drug to the target tissue meticulous or controlled manner.
Disparate nanocarriers used in drug delivery system are liposomes, solid lipid nanoparticles,
carbon nanotube, virus based etc. Application of these particle provide expeditious and
intense development in the field of medicine, health and technology. Nano formulations in
target drug delivery used to treat cardio-vascular disease, diabetics and cancerous tumours.
Many challenges observed are protein Corona, toxicity, stability etc. These challenges should
be solved to enhance the potential and make more effective in physical, chemical, and
therapeutic formulations.
Keywords: Organic and inorganic nano carriers, preparations and challenges.
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