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Abstract

A PROSPECTIVE STUDY ON “DRUG UTILIZATION STUDY ON ANTIBIOTICS USE IN LOWER RESPIRATORY TRACT INFECTION AND PNEUMONIA

*Saeideh Gomroki, Pharm D

ABSTRACT

Objective: To conduct study on medication safety study on antibiotics use in lower respiratory tract infection and pneumonia. Methodology: it was a prospective observational study conducted in: MEDICAL, ICU, HICU AND SURGERY WARDS of Bangalore Baptist hospital, conducted for a period of 6 months from March 2017 to October 2017. All inpatients who are diagnosed with LRTI or PNEUMONIA. The patient data collection was used to collect all the details like inpatient number, age, sex, social history, past history, laboratory data, diagnosis, therapeutic management. Fulfilling the inclusion criteria will be enrolled into the study and their prescriptions will be Analysed on daily basis. The prescription guidelines, Micromedex, interaction checker, drug interaction database and Shockley’s drug interaction book 8 edition. The drug interaction in prescription was collected and then compare with guidelines. When the analysis of prescription was completed then all data entered to the appropriate software and the results were gained. Result: Presence study showed from total of 100 patients were included in this study, alcohol/smoking history was confirmed in 66 (38 smoker and 28 alcoholic) patients. From these 53 (53%) of them diagnosed with LRTI, and 13 (13%) Of them with pneumonia. Also most of the patients had history of smoking (n=38) more than using alcohol (n=28). In this study the diagnosis of LRTI (Non Specific LRTI and Acute Bronchitis) accounted for 63% and pneumonia of 37% of total cases analysed. Further it was noted that a majority of the patients have association illness. Majority number was more in diabetic (61%), hypertension (46%) and asthma (18%). Conclusion: The majority of mild LRTI had a viral aetiology although mixed viral/bacterial infections were also common, and patients with a bacterial aetiology alone were not clinically distinguishable from those with viral LRTI In the present study bacteria were the most common cause of acute adult LRTI, occurring in 59% of patients, while respiratory viruses were detected in 41%.The present study find out that, in Medicine Department, for lower respiratory tract infections Antibiotics were commonly prescribed in poly-antibiotics form to treat the infection. The most commonly used antibiotic was ceftriaxone followed by azithromycin and piptaz. Prescribing by generic names has to be encouraged.

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