Abstract

A DETAILED INFORMATION ABOUT RESPIRATORY DISEASES CAUSED BY CORONA VIRUS AND ITS OUTBREAK – A REVIEW

Bandari Vamshi Krishna*, Thogaru Sandeep Reddy and Dr. Kadarla Rohith Kumar

ABSTRACT

Middle East respiratory syndrome (MERS) is a viral respiratory disease caused by a novel coronavirus (Middle East respiratory syndrome coronavirus, or MERS‐CoV) that was first identified in Saudi Arabia in 2012. Coronaviruses are a large family of viruses that can cause diseases ranging from the common cold to Severe Acute Respiratory Syndrome (SARS). SARS coronavirus (SARS-CoV) – virus identified in 2003. Typical MERS symptoms include fever, cough and shortness of breath. Pneumonia is common, but not always present. Gastrointestinal symptoms, including diarrhoea, have also been reported, whereas the Symptoms of SARS include fever, malaise, myalgia, headache, diarrhoea, and shivering (rigors). No individual symptom or cluster of symptoms has proved to be specific for a diagnosis of SARS. MERS-CoV is a member of the family Coronaviridae, As of January 20, 2017, the WHO had received reports from 27 countries of 1879 cases of laboratory confirmed MERS and at least 659 related deaths. As of Jan 23, 2020, confirmed cases were consecutively reported in 32 provinces, municipalities, and special administrative regions in China, including Hong Kong, Macau, and Taiwan. Seroepidemiologic studies have shown that antibodies to MERS-CoV are present in dromedary camels (Camelus dromedarius). The majority of severe MERS cases have occurred in adults older than 50 years of age who have coexisting conditions such as diabetes, hypertension, cardiac disease, obesity, chronic respiratory disease, end-stage renal disease, or cancer or in persons receiving immunosuppressive therapy. No vaccine or specific treatment is currently available, however several MERS-CoV specific vaccines and treatments are in development. Treatment is supportive and based on the patient’s clinical condition.

Keywords: Middle Eat Respiratory Syndrome, Mers-Cov, Severe Acute Respiratory Syndrome, Coronaviridae, Dromedary Camels.