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Abstract

REVIEW ON ISONIAZID DERIVATIVES AS ANTI-TUBERCULOSIS AGENT

*Hemant Farad and Dr. Deepali Jagdale

ABSTRACT

The appearance of tuberculosis and emergence of drug resistance requires focused attention and need to approve the various derivatives of isoniazid. Isoniazid is frontline drug is used for treatment of tuberculosis and it is key drug used for chemotherapy of tuberculosis. The present article contains compilation of various derivatives of isoniazid and their biological activity like anti-mycobacterial, antifungal, anti-viral activities. The emphasis is given on various reported synthetic routes for isoniazid derivatives which will be a help to researchers.

Keywords: Isoniazid, Antimycobacterial, Tuberculosis.


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