WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

FORMULATION AND EVALUATION OF FAST DISSOLVING FILM OF TRAMADOL HYDROCHLORIDE

Abhishek Saini*

ABSTRACT

Fast dissolving buccal film drug delivery system had rapidly gained acceptance as an important way of drug administration which are normally used for pharmaceutical and nutraceutical production. A fast dissolving buccal film drug delivery system has been described as a film that contain active ingredient which dissolves or disintegrates rapidly in saliva within few seconds and water is not needed for swallowing or chewing. Some drugs are absorbed well from mouth, pharynx and oesophagus because the saliva enters into the stomach for better absorption. In many of the cases, the bioavailability of these drug foams is significantly greater than compared to that of conventional tablet dosage form. Tramadol is a analgesic that act centrally and exhibit two complementary mode of action a therapeutic doses. Tramadol has the weak binding affinity to μ- and δ- opioid receptors and obstruct the serotonin and nor epinephrine uptake. Tramadol is used in the treatment of postoperative, dental and acute musculoskeletal pain and used as an additive for therapy of non-steroidal anti-inflammatory drug (NSAID) in osteoarthritis patients. Hence in chronic and severe pain, fast dissolving film of tramadol will be choice of patients over any other dosage form. The recent study is proceeded with a view to prepare fast dissolving film of tramadol through solvent casting method.

Keywords: Fast dissolving buccal film, Pharmaceutical, Nutraceutical, Bioavailability, Conventional.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More