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Abstract

COMPARATIVE CLINICAL STUDY OF AYURVEDIC TREATMENT AND CONVENTIONAL STANDARD TREATMENT IN THE MANAGEMENT OF ARDHAVABHEDAKA (MIGRAINE)-A RANDOMIZED CONTROLLED TRIAL

Shweta Mata*, Shivshankar Rajput, Hiten Maniar and D. B. Vaghela

ABSTRACT

Background: Ardhavabhedaka-hemicranial headache is a common disease that affects millions of individuals worldwide. The pain may be very bad and hurt so much that a person may have a hard time doing anything. The survey results suggested that both patients and physicians believe migraine treatment is elusive and that patients are becoming increasingly frustrated and dissatisfied with treatment outcomes. Ardhavabhedaka is a Tridoshaja and Vata kaphaja dominant disease according to Acharya Sushrut and Acharya Charak respectively. Its diagnosis is based on mainly clinical history. Material and Methods: In this study, eligible 107 patients were selected and randomly divided in two groups through computer generated randomization. Laghu Sutashekhara Rasa orally and Brihat Dashmoola Taila Nasya were given in trial group and Tab. Flunarizine was given in control group for 60 days. The primary outcomes measured were percentage changes in chief complaints, associate complaints and MIDAS of Ardhavabhedaka in comparison to both groups. Results: Regarding effect of therapy on Chief complaints in trial group, 83.21% relief was found in severity of headache, 82.53% in duration of headache and 82.06% in frequency of headache. In control group, 83.02% relief was found in severity of headache, 82.61% in duration of headache and 82.29% in frequency of headache. In MIDAS, 64.14% and 48.04% improvement was found in trial group and control group respectively. No any adverse drug reaction was found during whole study. Conclusion: Overall assessment of the therapy showed that administration of Laghu Sutashekhara Rasa and Nasya with Brihat Dashamoola Taila provided statistically significant improvement on subjective and MIDAS criteria.

Keywords: Ardhavabhedaka, Brihat Dashamoola Taila, Laghu Sutashekhara Rasa, Migraine.


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