WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

FORMULATION AND EVALUATION OF KETOCONAZOLE LOADED MICROSPONGE GEL FOR TOPICAL DRUG DELIVERY

Neha Sodiyal*

ABSTRACT

Ketoconazole is broad spectrum antifungal which shows fungi static activity and have biological half-life of 2 hours but it shows many gastrointestinal side effects when administered orally. To overcome these side effects, the aim of the present study was to formulate and evaluate ketoconazole loaded microsponge gel for topical delivery. Ketoconazole loaded microsponges were prepared by quasi emulsion solvent diffusion method using ethyl cellulose with varied drug polymer ratio. The prepared microsponges were characterized by SEM, FTIR, XRD, and evaluated for % drug content, particle size, % entrapment efficiency and in-vitro drug release. By all the results it was observed that the formulation F1 show excellent flow property and the formulation F5 shows better shape and morphology.

Keywords: Ketoconazole, Ethyl Cellulose, Carbopol gel, In – vitro drug release.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More