WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

NATURAL STARCHES AS PHARMACEUTICAL EXCIPIENTS: A REVIEW

Nina Varghese* and Dr. M. Komala

ABSTRACT

Starches present in tropical vegetables and fruits have served as a nutritive source of carbohydrate. Most of these crops grow in abundance with little or less agricultural assistance are present with starch in these which are gluten-free carbohydrates. When employed as an excipient can serve the criteria of gluten-free ingredient for the severely effected patients due to reactions created by the presence of gluten components. They have been studied for their excellent pharmaceutical excipient characteristics, such as filler, glidants, binder and disintegrant properties in formulations. Some of these starches can be substituted for commercially available chemically modified starches as excipients. It has been also studies that the modified versions of the native forms of these starches have properties that can be considered for including them as promising candidates in controlled drug delivery systems as well. Starch nanoparticles have been of great interest for drug delivery due to their relatively easy synthesis, biocompatibility, and vast amount of botanical sources. The modified forms of these starches had superior disintegrant properties to commercial superdisintegrant like sodium starch glycolate, which also indicate that they could be used as intragranular disintegrant in tablet formulations for which rapid release is desired as a substitute for the synthetic disintegrant. Their application as excipients can add value to some of these underutilized crops to provide starch with special properties for specific pharmaceutical need. This review summarizes the current knowledge on the starches extracted from tropical plants that has been studied for their potential usefulness as pharmaceutical excipients.

Keywords: Disintegrants, Super-disintegrant, tropical starches, gelatinization, polymer modification.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More