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Maheshwari V.*, Syam Prakash K. R., Priscilla Mary J., S. Haja Sherief and T. Sivakumar


Henoch-Schonlein Purpura (HSP) is a form of cutaneous small vessel vasculitis that can involve visceral organs and is associated with deposition of immunoglobulin A (IgA)-containing immune complexes. HSP may appear after a remote history of infection (often an upper respiratory tract infection) as a rash with palpable petechiae or purpuraprimarily in the legs and buttocks.[1] Vessel wall inflammation resulting in necrosis and tissue ischemia explain’s the clinical presentation of gastrointestinal hemorrhage and glomerulonephritis. A 40 years old male patient presented with B/L lower limb pain, rashes associated with an history of abdominal pain, elbow pain, ankle pain with palpable purpura on and off. These all are the main signs and symptoms of the disease. The case was diagnosed as HSP and was treated with injection Dexamethasone 2cc and T. Wysolone 20mg OD. The patient was also diagnosed with Type 2 diabetes mellitus, this HSP –triggered immunological abnormalities leading to insulitis may have lead to the development of diabetes.[2] Inflammation damages the blood vessels in the skin, intestine and kidney. Early diagnosis and treatment favor the better outcome in cases without any renal complications.

Keywords: Dexamethasone, Glomerulonephritis, Henoch-SchönleinPurpura, Immunoglobulin A, Palpable petechiae, Wysolone.

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