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Abstract

COLLAGEN SHIELDS- A NOVEL DRUG DELIVERY SYSTEM

Soji S.*, Prothibha Das, Minnu George and Anjali C. S.

ABSTRACT

Collagen shield basically consist of cross linked collagen, fabricated with foetal calf skin tissue and developed as a corneal bandage to enhance wound healing. They topically applied antibiotic conjugated with delivery. They determined the influence of size, molecular weight and number of amine, carboxylate and hydroxyl surface groups in several series of dendrimers. The residence time was longer for the solutions containing dendrimers with carboxylic and hydroxyl surface groups. The objective of this review article is to summarize information available on collagen dosage forms for drug delivery as well as to communicate an outline regarding current preparation of collagen available in market includes - collagen sponges for burns/wounds, mini-pellets and tablets, gel preparations in combination with liposomes for sustained delivery of drug, formulations for transdermal drug delivery, and nanospheres for gene delivery, collagen matrices for cell culture.

Keywords: Collagen; Drug delivery system; Opthalmology.


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