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Abstract

PREPARATION OF KARPOORADI CHURNA AND UDARKALP CHURNA BY USING THE INGREDIENTS TAKEN FROM LOCAL MARKET AND COMPARATIVE STANDARDIZATION

Kavita Jagdishji Mehta*, Dr. Priya Rao and Tushar Dukre

ABSTRACT

Introduction: Standardization of herbal formulations is important so as to assess the standard of medication, supported the concentration of their active principles. within the recent years there has been rise within the field of herbal medicine most of the tradition systems of drugs are accepted universally after standardization only. it vital to develop a vital methods to standardization of herbal related drugs. The study to standardization of Karpooradi Churna and Udarkalp Churna majorly focused on it area under WHO guidelines. In the last some years, the use of herbal drugs has been increased all over the world due to their huge therapeutic effect and less adverse effects as compared to other medicines. The rising use of herbal drug by the human is forcing the driving force to evaluate the health claim of these agents and to develop standards of quality, purity, safety and efficacy of the drug. Mostly herbal drugs are effective but due to adulteration and lack of standardization, the effectiveness of the herbal drug is decreased. So there is need of development of standardization parameters. In the standardization of the herbal drug the physical, chemical, biological, analytical parameters are carried out. It assures the quality, purity and safety of herbal drugs. Methods: This polyherbal Churna used treat the digestive and respiratory diseases. In-house preparation and also the marketed drug are standardized on the premise of organoleptic characters, physical characteristics, and physico-chemical properties. The set parameters were found to be sufficient to judge the churna and might be used as reference standards for the standard control/quality assurance laboratory of a Pharmaceutical house. For the standardization of the above formulations were done by evaluating the macroscopical, microscopical, powder flow properties, extractive values, Physicochemical characters, heavy metal content detection, qualitative and quantitive deter-mination of tannins and alkaloids and TLC finger print. Results: The parameters for both formulation complies with the standards. The flow properties are very poor. From the preliminary phytochemical test revealed the presence of various bioactive constituents.

Keywords: Karpooradi Churna, Udarkalp Churna, Standardization, TLC finger print, physico-chemical, polyherbal formulation.


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