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Amita Ajit, PhD*, Brijeetha P. D., M.Sc and Prashanth Varkey, M.S.


The extensive convenience and approval of synthetic compounds for addressing human health have quite a few side effects in addition to higher prices. Exploring natural bioactive compounds is of utmost interest and demand. Cardamom has been used traditionally for numerous therapeutic benefits and are relevant in the light of modern pharmaceutical perspective. This review inspects and presents consolidated information on the the phytochemical profile of cardamom seed and leaf extracts and superficially addresses the common extraction methods adapted in literature. An online survey was conducted on the traditional uses, phytochemical composition, and bioactive components of cardamom seed and leaf extract. Pertinent data were obtained from several electronic scientific databases (Science Direct, Elsevier, Web of Science, PubMed, Springer, ACS publications, Taylor and Francis, Wiley On-line Library and Google Scholar), and additional information was obtained from textbooks and local prints and scripts. Studies on the chemical composition and physico-chemical properties of the seed and leaf extracts of cardamomum depict a higher yield extract value from seeds than their leaves. Both seed and leaf extracts are known to have numerous therapeutic benefits as anti-bacterial, antimicrobial, anti-carcinogenic, anti-oxidant, anti-inflammatory and anti-ulcerogenic and gastroprotectory agents. Modern pharmacology researchers have made attempts in establishing many traditional uses of Cardamom. However, systemic studies on the phytocompounds which may possess new biological activities are lacking. Thus, more studies on the pharmacological mechanisms of its main active compounds need to be conducted keeping in mind therapeutic aspects, toxicity and adverse effects.

Keywords: Cardamom seed, Cardamom Leaf, Phytochemical composition, Bioactive compounds.

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