Abstract

A REVIEW ON RECENT ADVANCES IN COVID-19 MANAGEMENT

Sudhir Singh Gangwar*, Amita Tilak and Ranjana Sharma

ABSTRACT

The world has experienced several epidemics posing serious threat to global public health, including the 2002 severe acute respiratory syndrome (SARS) epidemic that caused 800 deaths out of about 8,000 cases, the 2009 H1N1 pandemic with 18,500 deaths, the 2012 Middle East respiratory syndrome (MERS) epidemic that caused 800 deaths out of 2,500 cases, the 2014 Ebola outbreak with 28,616 cases and 11,310 deaths, and the current coronavirus disease (COVID-19) pandemic with more than 1,565,292 deaths out of over 68,659,920 confirmed cases till now. and is affecting 213 countries all over the world. Coronavirus (CoV) disease-2019 (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome- CoV-2. The disease started in 2019 in Wuhan, China, and has spread globally, resulting in a pandemic. Common symptoms include fever, cough, and shortness of breath. Muscle pain, sputum production, and sore throat are less common symptoms. While the majority of cases result in mild symptoms, some progress to pneumonia and multiorgan failure. The deaths per number of diagnosed cases is estimated between 1% and 5%, on an average but varies by age and other health conditions. The infection is spread from one person to other via respiratory droplets, often produced during coughing and sneezing. It takes 2–14 days to develop symptoms from the day of exposure. Reverse transcription- polymerase chain reaction from a nasopharyngeal swab or oropharyngeal swab is the standard method of diagnosis. The infection can also be diagnosed from a combination of symptoms, risk factors, and a computerized tomographic scan of the chest showing features of viral pneumonia. Measures recommended to prevent the disease include frequent hand washing, maintaining safe distance from other people, and not touching one’s mouth eyes and nose. The use of masks is recommended for those who are suspected to have the virus and to their caregivers, besides the general public. As of now, there are currently more than 50 COVID-19 vaccine candidates in trials. WHO is working in collaboration with scientists, business, and global health organizations through the ACT Accelerator to speed up the pandemic response. Management of COVID-19 involves treatment of symptoms, supportive care, and experimental measures. In this review all relevant information about Corona virus management is given.

Keywords: Coronavirus; COVID-19; SARS-CoV-2; Infectious disease; Possible management.