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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.084

ICV : 90.8

WJPR Citation

	All	Since 2011
Citation	2903	2393
h-index	27	24
i10-index	68	60

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Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
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Abstract

EVALUATION OF ISOLATED PHYTOSTEROL FROM LEAVES OF HOLOPTELEA INTEGRIFOLIA (ROXB.) PLANCH FOR IT’S ANTIDEPRESSANT ACTIVITY IN EXPERIMENTAL ANIMALS

Ravindra C. Sutar*

ABSTRACT

Background: Majority of scientific documentation suggested promine nt role of Phytosterols towards Antidepressant activity. The main objec tive of the work was to evaluate Antidepressant activity of Holoptelea i ntegrifolia isolated Phytosterol (HIIP) from petroleum ether extract (P EHI) of leaves of Holoptelea integrifolia (Roxb) Planch. Methods: The Antidepressant activity of different doses of HIIP (10 and 30 mg/kg-p.o.) was evaluated using Forced Swim Test (FST) in mice. Results: HIIP-30 mg/kg was more potent than HIIP-10 mg/kg for showing Antidepressant activity. Conclusions: The results indicate that HIIP shows Antidepressant activity which was dose dependent.

Keywords: Forced Swim Test, Holoptelea integrifoila Isolated Phytosterol Depression, Fluoxetine.

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