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Abstract

ENDOPHYTIC BACTERIA AS A BUDDING RESERVE OF NEW ANTIBIOTICS

Aleena Roy*, Abdulla Shareef, Aiswarya Vasavan, Amal John James, Chitra C. Nair and Ammu S.

ABSTRACT

The human population is increasing with an alarming rate ecosystem are depreciating rapidly. A variety of new types of health issues are exploding up. For instance, increase in number of drug-resistant bacteria is a cause of concern. Research on antibiotics and other microbial natural products is decisive in the global fight against the growing problem of antibiotic resistance.[1] It is necessary to find new antibiotics to tackle this problem; and EB are one of the potential sources of novel antibiotics.[2] Antibiotics are useful compounds for treatment of human, farm animal and aquaculture infections. However, due to resistance development of pathogenic microbes to most of the useful antibiotics, there is a continuous necessity for new and powerful anti-infective compounds. This situation fosters the search for new compounds alternatives for the isolation of new compounds with antimicrobial activity. Endophytes are micro-organisms (bacteria and fungi) that live inside the living plant tissues for at least part of their life without causing any apparent disease symptoms in the host.[1] Endophytes thus represent a subset of microbes that reside in unique niches and, if explored properly, may prove to be a reservoir of bioactive principles.[3]

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