A REVIEW ON REPRODUCTIVE TOXICITY OF ORGANOCHLORINE PESTICIDES
Organchlorines; reproductive toxicity; endocrine disruption; male infertility.
ABSTRACT
A significant increase in the incidence of male infertility has been
described in the recent literature, raising questions about its causes.
Pesticides such as organophosphates, organochlorine, phthalates,
pyrethroids, carbamates and other substances from various industrial
uses and residues are among the main endocrine disruptors that cause
reproductive toxicity and male infertility. Organochlorines are a group
of various synthetic chemicals that include polychlorinated biphenyls
(PCBs), dibenzo-p-dioxiins and organochlorine pesticides. Human
exposure to organochlorine substances may occur through inhalation of
air, ingestion of food, water and skin absorption. Human exposure to
organochlorines may occur not only during adulthood but also during
prenatal and neonatal period. Many organochlorine pesticides are endocrine disrupting
chemicals, meaning they have toxic effects on the hormonal systems. This review provides
some specialized literature on work-related to organochlorine pesticides capable of causing
male infertility.
Keywords: Organchlorines; reproductive toxicity; endocrine disruption; male infertility.
[Full Text Article]