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Abstract

ROLE OF COMPLEMENT PATHWAY IN COVID-19 INFECTION & POTENTIAL TREATMENT STRATEGIES

Dr. Rachana Acharya*

ABSTRACT

Structure and mode of infection of Sars Cov 2 virus which is the causative agent of the ongoing pandemic is being elaborately studied. Every possible information regarding the mechanism of infection and the factors affecting the severity of the infection is crucial in understanding and deciding the combat strategies to prevent the infection from becoming severe and fatal. In this article the role played by complement components in increasing the severity of the COVID- 19 infection and the strategies therin to prevent the suspected outcomes have been elucidated. Complement components adversely affect the host due to the unique mechanism of the Sars Cov2 virus entry into the cell. Better understanding of this mechanism can be useful in deciding the strategies for preventing such severe reactions and thus proposing several novel treatment options.

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