REVIEW ARTICLE OF INDICATIONS, DOSE & DOSAGE AND USE OF RIFAXIMIN IN SPECIAL POPULATION
Rama Lakshmi Devadi*
ABSTRACT
Rifaximin, an oral antimicrobial, has many advantages because it is
selective intestine, has minimal adverse effects and is used for the
treatment of some diseases such as hepatic encephalopathy, irritable
bowel syndrome, travelers’ diarrhea, ulcerative colitis, Clostridium
difficile and acute diarrhea. Rifaximin in the form of 200 mg tablets is
commercially available. The crystalline a form is therapeutically safe
and effective. In most of the official compendia, rifaximin has no
monograph and in none of them is there a monograph for rifaximin
tablets. The literature, however, contemplates this gap with varied
methods. The literature presents some methods for evaluation of
rifaximin in both biological fluid and pharmaceutical product. High performance liquid
chromatography stands out for the evaluation of rifaximin. Most of the methods reported in
the literature are for pharmaceuticals products.
Keywords: .
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