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Ashwini Makadi*, D. V. Kulkarni, Pankaj Barapatre, Pooja Panchware, Shilpa Patil and Sneha Dwivedi


Modern science follows the concept of giving combination of two - three antibiotics along with other drugs like analgesic, antiinflammatory etc in treatment to cure all the complaints present in a disease. From ancient time, our Ayurvedic Acharayas have been using the same rule. They have introduced terms like “Mishraka ganas”, “Mahakashaya” which include combination of two or more drugs having same properties and mode of action. The drugs in particular combination acts on factors like dosha, dhatu, mala, as well as aagni, all of which are responsible for development of a particular disease. Panchakshiri, one of Mishraka gana mentioned by Bhavprakasha consist of tikta – Kashaya rasa which acts on kapha dosha, madhura vipaka and sheet virya which acts on pitta dosha and rakta dhatu. It has special use in yoni and garbhashaya vikara because it is prithvi mahabhoot pradhna which act on masapradhan avayva.

Keywords: Panchakshiri, Kashaya rasa, Shoshana, Stambhana, Ruksha – Grahi guna.

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