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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.084

ICV : 90.8

WJPR Citation

	All	Since 2011
Citation	2903	2393
h-index	27	24
i10-index	68	60

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World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
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Abstract

GCMS ANALYSIS AND ANTIBACTERIAL ACTIVITY OF COCOS NUCIFERA AND MUSA ACUMINATA AGAINST MULTI DRUG RESISTANT ESCHERICHIA COLI AND STAPHYLOCOCCUS AURESUS

I. M. Agnihotri*, S. S. Chari and D. G. Kadam

ABSTRACT

The present study was undertaken to determine antibacterial activity of Cocos nucifera and Musa acuminata leaf extracts against multi drug resistant Staphylococcus aureus and Escherichia coli. The leaf extracts of C. nucifera and M. acuminata were prepared by Continuous Soxhlet extraction and cold extraction method. Antibacterial activity was done by agar well diffusion method and MIC values were determined by using macro-broth dilution method. Antibacterial activity present in both the extracts; methanol extract of Musa acuminata and Cocos nucifera showed more antibacterial activity against multi drug resistant Staphylococcus aureus followed by the methanol extract of Cocos nucifera against Escherichia coli. GCMS analysis of both plant extracts showed presence of biologically active compounds 6- Octadecenoic acid, methyl ester, (Z)-, Neophytadiene and Squalene that possess pharmacologically potential activity. The Cocos nucifera and Musa acuminate leaf extracts may have therapeutic value in control of certain multidrug resistant bacterial pathogens.

Keywords: Antibacterial activity, GCMS analysis, Cocos nucifera, Musa acuminata, Staphylococcus aureus, Escherichia coli.

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