ANTIMICROBIAL ACTIVITY OF COCKROACH HEMOLYMPH
G. Manikyam and G. Swathi*
ABSTRACT
There is a need to discover new antimicrobial compounds with diverse
chemical structures and novel mechanisms of action because there has
been an alarming increase in the incidence of new and re-emerging
infectious diseases. The present study is aimed at evaluating the in
vitro antimicrobial activity of cockroach hemolymph against
Escherichia coli, Proteus, Pseudomonas, Staphylococcus and
Enterococcus. Streptomycin is used as a positive control. The
cockroach hemolymph was effective against all bacterial strains tested
when compared with positive control. The cockroach hemolymph has
shown the highest activity on Enterococcus and Staphylococcus with
2.0mm and 2.2mm of inhibitory zone respectively when compared to remaining strains. The
inhibitory zone of streptomycin is 2.4mm. The present investigation showed optimum
activity against Gram positive bacteria when compared to Gram negative bacteria. It had
thrown light on potential area to do research on cockroach hemolymph.
Keywords: Cockroach hemolymph, bacterial stains, inhibition zone.
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