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Abstract

ASSESSMENT OF THE RISK FACTORS AND THE EFFECT OF VITAMIN SUPPLEMENTS IN HYPERLIPIDEMIC PATIENTS

Dr. M. Rangapriya, *Neenu Wilson, Neeya Johny, S. Niranjana

ABSTRACT

Objective: The aim of the study was to compare the effect of vitamin supplements on the lipid profile of the hyperlipidemic patients and to assess their Cardiovascular risk factors by estimating the lipid profile. Study design and methodology: A prospective observational study was carried out for a period of six months with 91 hyperlipidemic patients after obtaining the ethical clearance. They were divided into three groups i.e., Control, Group A and Group B.The control group consisted of patients at the risk of developing hyperlipidemia or the newly diagnosed hyperlipidemic patients. Group A and group B consisted of patients taking Atorvastatin 20 or 10 mg/day and patients taking Atorvastatin 20 or 10 mg/day along with vitamin supplements respectively. Then the baseline lipid levels were calculated. At the end of 6 months, the lipid profile was measured again as the endpoint and compared. Statistical analysis of the collected data was done using Graph Pad Instat version 3.10. Results: In this study, we observed that the serum total cholesterol, LDL and triglyceride levels significantly reduced in those who were supplemented with vitamins along with statins. However, HDL levels didn’t show any significant improvement.Furthermore, male gender, old age (>50 years), social habits (unhealthy diet, smoking and alcohol consumption) or an underlying disease condition may also increase the CVD risk. Conclusion: The vitamin supplementation along with the statin therapy proves to be effective in lowering the increased lipid levels and further aid in reducing many of the cardiovascular diseases associated with high cholesterol levels.

Keywords: Hyperlipidemia, Anti-hyperlipidemic drugs, Vitamin supplements, Lipid profile.


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