Abstract

ANALYSIS OF QUANTUM-CHEMICAL INTERACTIONS OF FOLIC ACID AND SARS-COV-2 PROTEINS AS CAUSERS OF COVID-19

*PhD. Manuel González Pérez, PhD. María Liliana Hernández-Pérez, PhD. Alejandro Martínez-Velasco, MVZ. Gildardo Martínez-Castillo, ING. José Luis Trejo-Mirón and ING. Alberto Hernández-Ortiz

ABSTRACT

The adaptive immune system is important for the control of most viral infections. Currently, knowledge is available on the relationships between antigen-specific immune responses and sars-cov-2 infection. This research aimed to analyze the chemical-quantum interactions of Folic Acid (FAc) and the sars-cov-2 proteins as the cause of covid-19. Hyperchem software was used to carry out all simulations. The electron transfer coefficient theory (ETC) was used to calculate this coefficient to rank the interactions. 21 oxide-reduction quantum interactions are observed at the bottom of the quantum well. These interactions are of 20 pure amino acids (AAs) and FAc. The FAc has higher stability among all of them. Out of 441 possible interactions mixed with AAs vs. FAc, 21 oxidant interactions and 7 antioxidant interactions were found at the bottom of the quantum well. With this finding, it is concluded that FAc can render the aars-cov-2 proteins useless and cause the inactivation or death of this coronavirus. Furthermore, FAc is known to strengthen the immune system.

Keywords: Quantum-chemistry, folic acid, sars-cov-2, covid-19, electron transfer coefficient.