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Abstract

AN OVERVIEW ON ITS REPORTED SYNTHETIC DRUGS AND MEDICINAL PLANTS HAVING ANTIDIABETIC POTENCY

Ram Veer Maurya* Uday praksh Yadav, Sanni Gangwar and Dr. Atul Kumar

ABSTRACT

Type 2 diabetes mellitus (T2DM) is a global pandemic, as evident from the global cartographic picture of diabetes by the International Diabetes Federation. Insulin resistance or reduced insulin sensitivity and in some cases relatively reduced insulin secretion are characteristic of the type 2 diabetes mellitus. The body tissue is defective responsiveness to insulin resistance encompasses the insulin receptor in cell membranes. The specific defects are not known but diabetes mellitus is classified separately on the basis of various defects. Worldwide, approximately 200 million people are affected by type 2 diabetes mellitus, covering especially elderly people living in developed countries. First line treatment includes diet management and exercise with oral hypoglycaemic agents that helps in prevention of macrovascular and microvascular impedance.

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