SCREENING OF PHYTOCHEMICAL AND IN VITRO ANTIOXIDANT PROPERTY OF N-MIRACLE (POLYHERBAL FORMULATION).
Meenatchi Sundaram Angappan* and Jeyaprakash Karuppaiah
ABSTRACT
Antioxidants are substances that inhibit oxidation, and are capable of
counteracting the damaging effects of oxidation in body tissue. They
prevent damage caused by free radicals. They create a barrier from
free radial damage that results in decaying process of oxidation. Under
most pathological conditions there is generation of reactive oxygen
species and other free radicals. Polyherbal compounds are
concentrated pharmaceutical preparations of plants obtained by
removing active constituents with a suitable solvent, which is
evaporated away, and adjusting the residue to a prescribed standard.
The investigation of phytochemical compounds of the material
extracted in ethanol, methanol and water revealed the presence of
saponins, flavonoids, steroids, terpenoids, triterpenoids, alkaloids,
carbohydrates, anthraquinone, phenolic compounds, and glycosides.
Antioxidant activity of the N-Miracle (Polyherbal formulation) was also assessed by DPPH
assay, total antioxidant assay, superoxide radical scavenging assay, and reducing power
assay. They showed commendable antioxidant effect as that of the ascorbic acid. The
antioxidant properties were due to the presence of promising phytoconstituents in N-Miracle
(polyherbal formulation).
Keywords: Antioxidants, Reactive Oxygen Species, N-Miracle, Phytoconstituents, Polyherbal formulation.
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