A REVIEW ON GENERAL INTRODUCTION OF COMPREHANSIVE TWO-DIMENSIONAL GAS CHROMATOGRAPHY
Tara Shankar Basuri*, Parixit Parjapati, Vishal Modi and Nikita Thakor
ABSTRACT
A comprehensive two-dimensional gas chromatography (GC×GC) is
the most powerful method used for the separation of complex samples
which offers reliability in quantitative and qualitative analysis,
enhanced separation efficiency, information on the whole sample and
its components, ability to detect low quantities. These features are
essential for the analysis of complex samples, in which the number of
compounds may be large or the analytes of interest are present at trace
level. The aim of this work is to review the general information of
comprehensive two-dimensional gas chromatography. The present
review focuses on the basic principle, instrumentation of (GC×GC),
and its applications. The benefits of (GC×GC) are in the analysis of
complex samples easily overcome some minor drawbacks of techniques. The developed
instrumentation and methodology which performs well for environmental samples, and also
applied for other complex samples.
Keywords: (GC×GC), 2DGC, Principle, Instrumentation, Pharmaceutical Application.
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