Abstract

A REVIEW ON GENERAL INTRODUCTION OF COMPREHANSIVE TWO-DIMENSIONAL GAS CHROMATOGRAPHY

Tara Shankar Basuri*, Parixit Parjapati, Vishal Modi and Nikita Thakor

ABSTRACT

A comprehensive two-dimensional gas chromatography (GC×GC) is the most powerful method used for the separation of complex samples which offers reliability in quantitative and qualitative analysis, enhanced separation efficiency, information on the whole sample and its components, ability to detect low quantities. These features are essential for the analysis of complex samples, in which the number of compounds may be large or the analytes of interest are present at trace level. The aim of this work is to review the general information of comprehensive two-dimensional gas chromatography. The present review focuses on the basic principle, instrumentation of (GC×GC), and its applications. The benefits of (GC×GC) are in the analysis of complex samples easily overcome some minor drawbacks of techniques. The developed instrumentation and methodology which performs well for environmental samples, and also applied for other complex samples.

Keywords: (GC×GC), 2DGC, Principle, Instrumentation, Pharmaceutical Application.