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R. Kasirao*, B. Nagamani, P. Venkata Krishna, Sk. Khyrun Baji


In oral diagnostics, it has been a great challenge to determine biomarkers for screening and predicting the early onset of disease (prognostic tests) or evaluating the disease activity and the efficacy of therapy (diagnostic tests). An oral diagnostic tool, in general, should provide pertinent information for differential diagnosis, localization of disease and severity of infection. It serves as a basis for treatment planning and provides a means for assessing the effectiveness of therapy. Saliva is simple, non-invasive, readily available and easily collected without specialized equipment or personnel. For the past two decades, saliva has been increasingly evaluated as a diagnostic fluid for detecting breast cancer , oral cancer , caries risk, salivary gland diseases, periodontitis , and systemic disorders such as hepatitis C and the presence of human immunodeficiency virus (HIV).

Keywords: Saliva, Diagnostic agent, Diagnosis, Diseases.

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