SALIVARY BIOMARKERS AS A DIAGNOSTIC INDICATOR OF PERIODONTAL DISEASE - A REVIEW
Dr. R. Saranyan, MDS*, Dr. Rasila Sainu, Dr. D. Jayachandran, MDS, Dr. B, Manovijay, MDS, Dr. N. Sayee Ganesh, MDS, Dr. K. Priy, MDS,
ABSTRACT
A biomarker is a naturally occurring molecule or a gene by which a
particular pathological or physiological processes, diseases, etc can be
identified. Genetically a biomarker is "anything that can be used as an
indicator of a particular disease state or some other physiological state
of an organism". Periodontitis is a multifactorial disease of the
periodontium where the host releases a series of inflammatory
mediators .Saliva is being used as a diagnostic fluid for analysis of
periodontal disease as it is easy, rapid and non- invasive to collect ,
and readily abundant. This review deals with the various salivary
biomarkers of periodontal disease and the diagnostic aids available for
their detection.
Keywords: Periodontitis, saliva, biomarker, diagnostic aids.
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