Abstract

GROWTH, CHARACTERISATION, ANTIMICROBIAL AND ANTICANCER ACTIVITIES OF L ALANINE ADDED NICKEL SULPHATE CRYSTALS

P. Sagunthala*, V. Veeravazhuthi, P. Yasotha and P. Hemalatha

ABSTRACT

Nickel Sulphate hexa hydrate (NSH) is hydrogen bonded crystal having a wide range of applications in various fields. An attempt was made to understand the effect of L alanine on NSH crystals. The crystals were grown by slow evaporation method in aqueous solution at room temperature. The grown crystals were characterized structurally, optically, thermally and biologically. X-ray diffraction studies proved the crystalline nature of the grown compound and it belongs to monoclinic structure. FTIR analysis confirmed the presence of various functional groups in the grown crystal. The results of UVvisible spectroscopy shows that the grown crystal has good optical transparency in the wavelength range 223-319 nm. Thermo gravimetric analysis proved that the crystal is stable up to 110ºC. Hence this crystal may be used in UV filters even at elevated temperatures. The grown crystal was evaluated for its biological efficacy and found to exhibit pharmacological properties such as antimicrobial and anticancer.

Keywords: Ultraviolet filter, X-ray diffraction, FTIR and UV spectrum, Thermal stability, antibacterial, anticancer.