―FORMULATION DEVELOPMENT & EVALUATION OF FAST DISSOLVING TABLET OF RIZATRIPTAN BENZOATE”
Kishor Rodge*, R. S. Moon and Swapnil Waghmare
ABSTRACT
The purpose of this investigation was to to develop fast dissolving
tablet of Rizatriptan Benzoate using various concentration of
disintegrants and superdisintegrants along with directly compressible
excipients. Rizatriptan benzoate use to treat migraines. Fast dissolving
tablet of Rizatriptan benzoate containing crospovidone-xl,
croscarmellose sodium, avicel PH-102, aspartame, magnesium
Stearate, Aerosil, menthol, pearlitol SD-200 The formulation were
evaluated for disintegration time, in vitro dissolution, hardness,
friability, weight variation and thickness, water absorption ratio.
Keywords: superdisintegrant, Fast dissolving Tablet, Migraine, Rizatriptan benzoate.
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