World Journal of Pharmaceutical Research (WJPR) has indexed with various reputed international bodies like : Index Copernicus , Google Scholar , EBSCO Publishing Inc (Academic Search Complete), USA , Indian Science Publications , Urlich's Periodicals Directory, Proquest, UK , NewJour-Georgetown University Library, USA , SOCOLAR, China , eGranary Digital Library, USA , CAS (A Division of American Chemical Society) USA , Research Bible, Fuchu, Tokyo. JAPAN , Science Central, USA , Kaohsiung Medical University Library, CHINA , VIKAS PSOAR (Pharmaceutical Sciences Open Access Resources) , Scopus ((Elsevier Products in process) , EMBASE (Elsevier Products, in process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , Thomson Reuters, USA (in process) , Genamics JournalSeek (In Process) , Hinari Research , Geneva Foundation for Medical Education and Research, Switzerland (In Process) , Lupton Library, (In Process) , Polish Scholarly Bibliography , Virtual Library Pharmacy, Medicine and Health, Biosciences , UDLedge Science Citation Index , Global Impact Factor (0.652) , International Impact Factor Services , Directory of Research Journal Indexing (DRJI) , Universal Impact Factor (0.9861) , International Scientific Indexing, UAE , SJIF Impact Factor (5.045) , Scholar Steer, (Under Process) , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , InfoBase Index (In Process) , Scholar Article Impact Factor, SAIF , CiteFactor , Journal Index (JI, Under Process) , Indian citation Index (ICI) , Indian Citation Index (ICI) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Eurasian Scientific Journals Index (ESJI) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Journalseek Database , Pubmed Database [NLM ID:101644668] (Under Process) , IP Indexing (Under Process) , EBSCO, USA , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) ,

WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.084

ICV : 90.8

WJPR Citation

	All	Since 2011
Citation	2903	2393
h-index	27	24
i10-index	68	60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Track Your Article

Abstract

THE H+/K+ ATPase INHIBITORY ACTIVITY OF ETHANOLIC EXTRACT OF DIOSPYROS PANICULATA Dalz BARK

Mithun K. Sebastian* and Shan P. Mohammed

ABSTRACT

The Diospyros Paniculata is a folkforic medicine which has been used in Ayurveda and Siddha system of medicines. It has been commonly used in the treatment of ulcer, burns, poisoning etc. The present study is conducted to evaluate the In vitro H+/K+ ATPase inhibitory activity of ethanolic extract of Diospyros Paniculata (EEDP). H+/K+ ATPase inhibition assay was performed by using different concentration of EEDP ranging from 10-50μg/ml and % inhibition calculated which is compared with the standard drug lansoprazole. The results obtained indicate that the EEDP has significant In vitro H+/K+ ATPase inhibitory activity (P<0.001).IC 50 value of the EEDP is 26μg/ml and the IC 50 value of Standard drug lansoprazole is 18μg/ml. The ethanolic extract of Diospyros Paniculata is having good H+/K+ ATPase inhibitory action.

Keywords: Diospyros Paniculata, In vitro, H?/K+ ATPase.

[Full Text Article]