Abstract

ICP-MS, ICP-AES AND FLAMEPHOTOMETRIC QUANTITATIVE DETERMINATION AND VALIDATION OF ELECTROLYTES FROM HERBAL CARDIOL VATI

Raju P. Suryawanshi* and Sudhir S. Kamat

ABSTRACT

Cardiol vati is one of the most popular herbal medicines in Indian market for Cardiac patients. Minerals and Electrolytes are naturally occurring elements present in herbal medicines. The vati content Manganese(Mn), Calcium(Ca), Magnesium(Mg), Sodium(Na) and Potassium(K). Though they are essential elements it is utmost necessary to determine the quantitatively because it most effects on heart and kidney. The daily requirement of minerals, Electrolytes is in micrograms, but there is no proper method to detect the accurate concentration of minerals, electrolytes present in herbal medicines. Herbal medicines require implementation and good manufacturing practices and effective quality control methods. In addition, various parameters such as dosage, stability, toxicity, chemical factors such as pesticides residue, aflatoxin content and heavy metals contamination and age should be taken in to consideration. Diseases occur due to their deficiency and toxicity due to overdose. These minerals can bind to vital cellular components and interfere with their normal functions. In human being, these minerals can cause severe physiological and health effects. The rapid development of metro cities in developing as well as in developed countries it causes adverse life style effects like unhealthy food, pollutions and a sedentary job and transportation mode are likely to be risk factors for cardiac diseases. Electrolytes are needed for metabolism, normal cellular activities and help to maintain the acid-base balance. Herbal medicines required standardization with implementation and constant review of technical standards of herbal product and effective quality control methods. Therefore, it is thought necessary about the efficacy and standardization of Cardiol vati. Hence in present study Herbal Cardiol vati was scanned for the analysis of Electrolytes like Manganese(Mn), Calcium(Ca), Magnesium(Mg), Sodium(Na) and Potassium(K). These Electrolytes can cause several physiological and health effects. These Electrolytes can determine by quantitatively and validated by using modern technique such as ICP-MS, ICP-AES and Flame photometer.

Keywords: Cardiol vati, Standardization, Herbal medicine, Electrolytes, ICP-MS, ICP-AES and Flame photometer.