Abstract

TABLET MANUFACTURING BY GRANULATION METHOD AND COMMON PROBLEMS IN TABLET MANUFACTURING

Karbhari Vilas N.* and Warad T. A.

ABSTRACT

In the direct compression method of tablet production, dry ingredients are thoroughly mixed and then compressed into tablets. This eliminates the drying steps associated with the wet granulation method. It also reduces the higher costs involved in wet granulation including increased equipment, labor, time, process validation and energyexpenditure. The tableting mixture prepared by three techniques Wet granulation, Dry granulation or direct compression.

Keywords: Direct Compression, Wet Granulation, Dry Granulation, Stability.