EXPLORATION OF ANTIMUTAGENICITY OF PLANT MEDIATED SYNTHESIS OF SILVER NANOPARTICLES USING THE PLANT EXTRACT Anredera Cordifolia
Rajathi.K* and S.Suja
ABSTRACT
Nanotechnology is a rapidly growing field with its numerous
applications in science and technology. Mutation is an important factor
in inducing carcinogenesis. This study reports that the antimutagenic
activity of the plant extract Anredera Cordifolia is used to reduce the
exposure of mutation and its inducing agent. The antimutagenic
activity was assessed in the silver nanoparticle synthesized plant
extract of Anredera Cordifolia. The synthesized silver nanoparticle
was characterized using SEM analysis, X-Ray diffraction and UVVisible
spectroscopy. Ames test was performed. Antimutagenic
activity of the silver nanoparticle synthesized plant extract Anredera
cordifolia was tested against Salmonella typhimurium strains TA 98,
TA 100 using direct acting mutagens and those needing activation by Ames test.
Determination of antimutagenicity against mutagens was assayed using plate incorporation
method. The activity indicates that silver nanoparticles of Anredera Cordifolia are capable of
redending antimutagenic efficiency.
Keywords: Silver nanoparticle, antimutagenic, Anredera cordifolia.
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