Abstract

EXPLORATION OF ANTIMUTAGENICITY OF PLANT MEDIATED SYNTHESIS OF SILVER NANOPARTICLES USING THE PLANT EXTRACT Anredera Cordifolia

Rajathi.K* and S.Suja

ABSTRACT

Nanotechnology is a rapidly growing field with its numerous applications in science and technology. Mutation is an important factor in inducing carcinogenesis. This study reports that the antimutagenic activity of the plant extract Anredera Cordifolia is used to reduce the exposure of mutation and its inducing agent. The antimutagenic activity was assessed in the silver nanoparticle synthesized plant extract of Anredera Cordifolia. The synthesized silver nanoparticle was characterized using SEM analysis, X-Ray diffraction and UVVisible spectroscopy. Ames test was performed. Antimutagenic activity of the silver nanoparticle synthesized plant extract Anredera cordifolia was tested against Salmonella typhimurium strains TA 98, TA 100 using direct acting mutagens and those needing activation by Ames test. Determination of antimutagenicity against mutagens was assayed using plate incorporation method. The activity indicates that silver nanoparticles of Anredera Cordifolia are capable of redending antimutagenic efficiency.

Keywords: Silver nanoparticle, antimutagenic, Anredera cordifolia.