Abstract

IN-VIVO ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY OF ETHANOLIC EXTRACT OF CANTHIUM PERVIFLORUM

Pottendla Srikanth* and Yaparthi Suneetha

ABSTRACT

Inflammation is a defensive response triggered when the body is threatened by for examplepathogens, damaged cells or irritants. Inflammatory diseases include rheumatoid arthritis, atherosclerosis, Alzheimer’s, asthma, psoriasis,multiple sclerosis, and inflammatory bowel diseases, and many of these inflammatory diseases are becoming common throughout the world Pain is an unpleasant subjective experience that is the net effect of a complex interaction of the ascending and descending nervous systems involving biochemical, physiological, psychological, and neocortical processes. Pain can affect all areas of a person’s life including sleep, thought, emotion, and daily activities.The present study was carried out to evaluate the anti inflammatory and analgesic activity of a natural plant canthium perviflorum fruits ethonolic extract on male albino rats. A group of animals will be examined for health and healthy Wistar rats will be selected for the study & will be randomly assigned to different groups based on the body weight.Phytochemical screening and pharmacological evaluation on rats has been done and it has shown the significant anti inflammatory and analgesic activity and it is further requires elaborated studies on the plant.

Keywords: Diclofenac, Paw edema method, Carboxy methyle cellulose, Formalin.