WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60


Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here


Track Your Article



Manoj Kumar Katual* and S.L. Harikumar


In current scenario, Brain tumors constitute an unsolved clinical problem although significant strides have been made in the treatment of many other cancer types. The incidence of primary brain tumors in the United States has been estimated at approximately 43,800 per year and 18,500 of these are expected to be malignant. Currently brain tumors account for at least 12,690 deaths in the United States yearly. Therapy of brain tumor still remains a challenge despite of recent improvements in surgery and multi adjuvant therapy. Drug therapies of brain tumor have been particularly inefficient, due to the blood-brain barrier and the non-specificity of the potentially toxic drugs. The nano-arriers has emerged as a potential vector for brain delivery, diagnosis & able to overcome the problems of current strategies. Moreover, multi-functionality can be engineered into a single platform so that it can provide tumor specific detection, treatment, and follow-up monitoring. Such multitasking is not possible with conventional technologies. The recent advances in nano-carrier based detection and treatment of brain tumor. The advantages of nano-carriers based delivery and the types of nano-carrier systems under investigation are described, as well as their applications. A broad spectrum of biocompatible nanoparticles, either synthesized or purified from the living body, has been investigated so far. The types of nanoparticles include polymeric, ceramic and metallic matrixes, polymeric micelles, liposomes and dendrimers. For cancer imaging, various types of nanoparticles have been investigated for MRI, optical imaging and ultrasound imaging. Several nanoparticle formulations have been clinically approved for MRI.

Keywords: MRI, Brain delivery, Nanoparticles, Brain cancer, Blood-brain barrier.

[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More