Abstract

INVIVO ANTI-INFLAMMATORY ACTIVITY STUDIES ON SIMAROUBA GLAUCA LEAVES

Jibi Antony*, Dr. D. Gnanasekaran and Anupriya Thomas

ABSTRACT

The aim of the study is to carry out the in vivo anti‐inflammatory activity on leaves of Simarouba glauca. The in-vivo anti- inflammatory activity of the ethanolic extract Simarouba glauca has been done by on croton oil induced ear edema method. Topical application of croton oil promoted an increase in the thickness of the ear. Upon application of the ethanolic extract (1%, 3% and 5%), the result was observed as 23.53%, 45.92% and 59.79% and standard 72.64%. The maximum inhibition of croton oil-induced ear edema was observed as 59.79% when compared with standard. The ethanolic extract possess better activity which was comparable to the standard drug (Dexamethasone cream).

Keywords: anti?inflammatory activity, dexamethasone cream, medicinal plant.