INVIVO ANTI-INFLAMMATORY ACTIVITY STUDIES ON SIMAROUBA GLAUCA LEAVES
Jibi Antony*, Dr. D. Gnanasekaran and Anupriya Thomas
ABSTRACT
The aim of the study is to carry out the in vivo anti‐inflammatory
activity on leaves of Simarouba glauca. The in-vivo anti- inflammatory
activity of the ethanolic extract Simarouba glauca has been done by on
croton oil induced ear edema method. Topical application of croton oil
promoted an increase in the thickness of the ear. Upon application of
the ethanolic extract (1%, 3% and 5%), the result was observed as
23.53%, 45.92% and 59.79% and standard 72.64%. The maximum
inhibition of croton oil-induced ear edema was observed as 59.79%
when compared with standard. The ethanolic extract possess better
activity which was comparable to the standard drug (Dexamethasone cream).
Keywords: anti?inflammatory activity, dexamethasone cream, medicinal plant.
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