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World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
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Dr. Sudhir Mehta*


Background: Pleural effusion is a common and at times life threatening infection of pleural cavity. The microbiological profile of organisms causing pleural effusion is always evolving; hence it needs constant surveillance to decide upon the antibiotic regimen and also the treatment protocol. Objective: is to evaluate the etiology, clinical profile and outcome of children with Pleural effusion. Material and methods: A total 30 admitted patients of Pleural effusion between the age of 6 months to 12 years during the period from 2014 to 2015 were included in study. A thorough history followed by clinical examination was done. Finally all enrolled patient underwent CXR and blood investigations and pleural fluid analysis were done. Results: Male to female distribution was 18:12. Most (63.75%) patients belonged to 1-5 year age group. Fever (95%) was most common presenting symptom followed by cough and breathlessness in 92% and 83% respectively. Bilateral involvement seen in 8.5% and 7% had H/O of Koch’s contact. 18% had hydro-pneumothorax on CXR. Pleural fluid culture and blood culture were positive in 20% and Staphylococcus aureus being the commonest organism isolated from both. Intravenous Amoxyclav was most the common antibiotic used at presentation in 70.5%. A total 25% patient required more than 21 days of IV antibiotics.60% patients required second antibiotic in view of non-improvement with ceftriaxone was most common antibiotic used in these cases. Conclusion: Treating unit should review antibiotic policy periodically based on culture report and clinical outcome.

Keywords: Pleural effusion, Clinical outcome, IV antibiotic.

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