SELF-EMULSIFYING DRUG DELIVERY SYSTEM
Shivaji Talegave*
ABSTRACT
Self- emulsifying drug delivery system are the unique mixture of oil,
solvent surfactant, co-surfactant, co-solvents. These are the effective
approach to solving the solubility of poorly soluble drug. From couple
of years aqueous solubility is biggest issues to the formulator for
formulation and development of novel drug delivery. SEDDSs are
Good strategy for enhancement of oral absorption and bioavailability
of BCS class 2 and class 4 drugs. For these system oral route is most
convenient than other route. Requirement of this system is due to poor
solubility and oral absorption of highly lipid soluble drug. Those drug which is formulated by
SEDDS will have good pharmaceutical market. These system have ability to form
emulsification with the solid as well as liquid dosage form .SEDDS are very quickly
dispersed in the gastro-intestinal fluid and making micro or Nano-emulsion containing
solubilized drug. These article covers formulation, Evaluation, future aspect and application
part of self-emulsifying drug delivery system.
Keywords: Self Emulsifying Drug Delivery System (SEDDS), Solubility, bioavailability
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