Abstract

CONCEPTUAL STUDY OF CUMULATIVES POISONS WITH SPECIAL REFERENCE TO DUSHI VISHA.

Dr. Dinesh Kumar Kumawat*, Dr. Anita Sharma and Dr. Madhu Pathak

ABSTRACT

The substances which are not excreted from the body & tend to pile-up in different organs of the body for a long period is called as Cumulative Poison. They are not causing any toxic effect when entering in low doses. However, when such poisons enter the body over a long period, even in low doses, may ultimately cause harm when their concentration in different tissues reaches high level due to their cumulative effect. Bioaccumulation refers to the accumulation of substances, such as pesticides, or other organic chemicals in an organism. Bioaccumulation occurs when an organism absorbs a toxic substance at a rate greater than that at which the substance is lost. Thus, the longer the biological half-life of the substance the greater the risk of chronic poisoning, even if environmental levels of the toxin are not very high. Many bioaccumulative chemicals are fat-soluble so that they tend to reside primarily in fat deposits or in the fatty substances in blood. This explains why fat-soluble bioaccumulative chemicals are often found at elevated levels in fat-rich breast milk. But bioaccumulative substances may also be deposited elsewhere, including bone, muscle, or the brain. Dushi Visha is one of the unique concept explained in Ayurveda. It is a type of toxin which remains inside the body for long & then produces various ill effects on the body. The ancient concept of dushi visha seems to be more relevant in this context. our acharyas has defined dushivisha as intake of toxic drug which are less potent remains in dormant state within the body for year together without causing any harm to the body.

Keywords: cumulative Poison, Dushivisha.