SCREENING OF ANTIOXIDANT AND ANTICANCER ACTIVITY IN CROTON BONPLANDIANUM LEAF AND STEM CRUDE EXTRACTS.
Dr. S. R. Divya and Dr. A. Chandra Mohan*
ABSTRACT
The phytoconstituents were remarkably higher in the leaf than the stem
of Croton bonplandianum. Antioxidant activity of Croton
bonplandianum was elucidated by DPPH. The methanolic extracts of
both the leaf and the stem has the elevated levels of scavenging
property when compared to the other extracts. The cytotoxicity study
was carried out for plant the leaf and stem extracts of Croton
bonplandianum. These extracts were screened for its cytotoxicity
against HepG2 cell lines at different concentrations to determine the %
of Viability and % of toxicity by MTT assay. The results are
graphically represented and the percentage of viability was found to
decrease and the percentage of toxicity was found to be increasing with
increasing concentration of the extracts.
Keywords: Anticancer, Antioxidant, Plant extract, DPPH and MTT assay.
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