INHIBITION OF LOW DENSITY LIPOPROTEIN OXIDATION AND PROTECTION OF DNA CLEAVAGE BY PHENOLIC EXTRACT FRACTION OF OCIMUM BASILICUM
P. Karthiga and M. Bimonisha, Dr. A. Chandra Mohan* and K. Nisha
ABSTRACT
The medicinal plant of Ocimumbasilicum leave have the valuable plant
constituents for the scavenging of free radicals because of their
phenolic hydroxyl groups. That the amount of polyphenolic
compounds increases, the antioxidant activity also increases. The
present study demonstrates that the polyphenolic extract of
Ocimumbasilicum leave scan protect the body from oxidative stress
from ROS, which may be due to the phyto-chemicals in the form of
polyphenols that occur in the plant. However, additional studies are
necessary to develop a method for the fractionation and identification
of polyphenols and to determine the most active antioxidant
compounds in the polyphenolic extract free radical scavenging assay
were carried out.
Keywords: Antihemolytic, methanolic extract, hLDL, H2O2 and NA.
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