ROLE OF TRACE ELEMENTS AND ANTIOXIDANTS IN THE PATIENTS OF PROSTATE CANCER
Sunil Kumar*, Shikhaa Mahajan, Suvarana Prasad, Neeru Bhaskar, Shilpa Rattan, Rooma Devi
ABSTRACT
Cancer is defined as a relatively autonomous growth of tissues. The
cells which divide abnormally having uncontrolled growth. The agent
that is responsible for causing cancer is termed as carcinogen and the
process of cancer development is referred to as carcinogenesis and the
agents which increases the frequency with which normal cells are
converted to transformed cells are said to be carcinogenic. In addition
to being most commonly encountered cancer among men, prostate
cancer is second leading cause of death among cancers, following lung
cancer Some trace elements like zinc, iron and copper play important
role in the development or proliferation of tumor cell. It has been
illustrated that in case of prostate cancer, cellular level of Zinc decreases, in contrast of which
cellular level of copper and iron increases. Alteration in the levels of these trace elements
causes increased growth and proliferation of the cells, which on progression acquire
malignant properties. And thus they play an indirect role in development of prostate cancer.
Thus variation in the levels of these trace elements may have a causative effect on prostate
cancer.
Keywords: Prostate Cancer, Trace Element- Zinc(Zn), Iron(Fe), Copper(Cu), Reactive Oxygen Species(ROS), Antioxidant.
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