Abstract

REACTIVE OXYGEN AND NITRIC OXIDE SCAVENGING ACTIVITY OF APLOTAXIS AURICULATA RHIZOMES

C. Arunmathi and T. Malarvili*

ABSTRACT

The Present investigation was to screen the antioxidant activity in order to find novel antioxidants in future pharmaceutical formulations. The methanolic extract of Aplotaxis auriculata rhizome extract (AARE) was screened for in-vitro antioxidant activity by DPPH radical scavenging assay, total antioxidant assay, superoxide anion scavenging activity, nitric oxide scavenging activity, Fe2+ chelating activity and reducing power assay at different concentrations. From the results, the AARE contains active biocompounds which participate in various pathophysiology of diseases including stress, cardiovascular diseases, inflammation, ageing, diabetes etc. Thus, this study performs experimental evidence on AARE as natural antioxidant due to its capacity to scavenge ROS & RNS and protect cells or organism from oxidative damage and thus could be effective against oxidative stress.

Keywords: Antioxidants, Aplotaxis auriculata, oxidative stress and Phytochemicals.