REACTIVE OXYGEN AND NITRIC OXIDE SCAVENGING ACTIVITY OF APLOTAXIS AURICULATA RHIZOMES
C. Arunmathi and T. Malarvili*
ABSTRACT
The Present investigation was to screen the antioxidant activity in
order to find novel antioxidants in future pharmaceutical formulations.
The methanolic extract of Aplotaxis auriculata rhizome extract
(AARE) was screened for in-vitro antioxidant activity by DPPH
radical scavenging assay, total antioxidant assay, superoxide anion
scavenging activity, nitric oxide scavenging activity, Fe2+ chelating
activity and reducing power assay at different concentrations. From the
results, the AARE contains active biocompounds which participate in
various pathophysiology of diseases including stress, cardiovascular
diseases, inflammation, ageing, diabetes etc. Thus, this study performs
experimental evidence on AARE as natural antioxidant due to its
capacity to scavenge ROS & RNS and protect cells or organism from
oxidative damage and thus could be effective against oxidative stress.
Keywords: Antioxidants, Aplotaxis auriculata, oxidative stress and Phytochemicals.
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